Uric Acid: The Oxidant-Antioxidant Paradox
نویسندگان
چکیده
منابع مشابه
Antioxidants and respiratory disease: the uric acid paradox.
In clinical practice, high blood concentrations of uric acid (UA) are generally thought to be a bad thing—primarily because of the risk of gout, but also because individuals with high UA concentrations are at increased risk of cardiovascular disease, metabolic syndrome and hypertension; these associations may reflect the fact that, under certain circumstances, UA can be pro-oxidant. Perhaps les...
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The aim of this article is to review the role of uric acid in the context of antioxidant effects of wine and its potential implication to human health. We described and discussed the mechanisms of increase in plasma antioxidant capacity after consumption of moderate amounts of wine. Because this effect is largely contributed by acute elevation in plasma uric acid, we paid special attention to w...
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In order to survive in an oxygen environment, aerobic organisms have developed numerous mechanisms to protect against oxygen radicals and singlet oxygen. One such mechanism, which appears to have attained particular significance during primate evolution, is the direct scavenging of oxygen radicals, singlet oxygen, oxo-haem oxidants and hydroperoxyl radicals by uric acid. In the present paper we...
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Hyperuricemia is known to be associated with the presence of cardiovascular and metabolic syndrome and with the development of incipient kidney disease and an accelerated renal progression. However, an elevated uric acid level was not generally regarded as a true etiology or mediator, but an indicator of these diseases. Uric acid has recently regained the clinical interest and popularity based ...
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Selenium is an essential biological trace element. Adult daily intake of selenium should be approximately 100 µg per day. This compound has a two-sided effect depending on its concentration. A selenium-deficient diet is associated with various endemic diseases, including cardiomuscular malfunctions, osteoarthritis, cancer and viral infections that lead to premature death. These defects are prev...
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ژورنال
عنوان ژورنال: Nucleosides, Nucleotides and Nucleic Acids
سال: 2008
ISSN: 1525-7770,1532-2335
DOI: 10.1080/15257770802138558